Can PCOS Cause Ovarian Cancer? Understand the Possible Link

Dr. Vrundali Kannoth•5 minutes•06 Nov 2025
Can PCOS Cause Ovarian Cancer? Learn About the Connection
If you're a woman, chances are you’ve heard of PCOS, maybe from your doctor, your mom, or that one friend who’s been dealing with it for years. It’s one of the most common hormonal disorders affecting women today, with 1 in 8 women being afflicted with this illness globally.

To clear the confusion, this article breaks down the link between PCOS and ovarian cancer and can PCOS lead to ovarian cancer. We’ll also share ways you can protect your health through early awareness and preventive care.
What is PCOS?
PCOS, or Polycystic Ovary Syndrome, is a common hormonal disorder that affects how a woman’s ovaries work. It happens when the body produces higher-than-normal levels of male hormones (androgens), which can interfere with ovulation and cause irregular periods.
Tiny fluid-filled sacs called follicles may also form in the ovaries, leading to hormonal imbalances and fertility issues.
Here are some common symptoms to look out for:
- •Irregular or missed periods
- •Excess hair growth on the face or body
- •Acne or oily skin
- •Weight gain or trouble losing weight
- •Thinning hair or hair loss on the scalp
- •Difficulty getting pregnant
Recognising these symptoms matters as it allows early diagnosis, better hormonal control, and helps avoid confusion between PCOS and ovarian cancer.
Causes of PCOS
Other than high androgen levels, several other factors contribute to the development of PCOS. It’s rarely caused by a single issue alone; usually, a combination of hormones, genes, and lifestyle factors work together to trigger this condition.
Here are some of them:
- •Insulin resistanceWhen the body becomes less responsive to insulin, blood sugar levels rise. To compensate, the pancreas produces more insulin, which in turn stimulates the production of excess androgens. This cycle disrupts ovulation and worsens PCOS symptoms over time.
- •Genetic factorsIf your mother or sister has PCOS, your chances of developing it increases - about 20% to 40% of women with PCOS have an affected first-degree relative. Family-linked hormonal patterns and metabolic traits often influence how the condition presents and progresses.
- •Low-grade inflammationMany women with PCOS show signs of mild, ongoing inflammation, meaning the immune system is slightly more active than normal, even without illness. This can interfere with the ovaries' function and may impact long-term hormonal balance and ovarian health.
How does PCOS lead to ovarian cancer
While we’ve discussed the root causes of Polycystic Ovary Syndrome (PCOS), those same mechanisms may help explain the answer to can PCOS cause ovarian cancer, even if it doesn’t guarantee it.
1. High estrogen levels
Women with PCOS often don’t ovulate regularly, which means the body stays exposed to estrogen for longer periods. This “unopposed estrogen” can sometimes cause abnormal cell growth in the ovaries.
2. Insulin resistance
In PCOS, the body becomes less sensitive to insulin, so the pancreas produces more of it to keep blood sugar levels stable. This excess insulin can overstimulate the ovaries, causing them to produce more androgens.
3. Chronic inflammation
With the body’s immune system remaining mildly active in PCOS, it releases inflammatory chemicals, such as cytokines and CRP. These chemicals can then damage healthy ovarian cells and create oxidative stress (a process where unstable molecules harm DNA)
4. Obesity
Obesity often co-exists with PCOS; adipose tissue amplifies estrogen production, raises insulin levels, and triggers inflammation. Each of those in turn is a known risk factor for ovarian cancer.
Preventive steps for PCOS and ovarian cancer risk
So, can PCOS cause ovarian cancer? Although research hasn’t proven this, certain PCOS-related changes can increase the risk. Taking preventive steps early can make a major difference.
Here’s what helps most:
1. Healthy diet and weight management
A balanced diet and healthy weight are key to controlling PCOS symptoms and lowering ovarian cancer risk. Excess weight increases insulin resistance and estrogen levels, both of which can contribute to hormonal imbalances.
- •Limit processed sugars and refined carbs.
- •Include lean proteins and healthy fats (like fish, nuts, and olive oil).
- •Exercise regularly - even 30 minutes a day can make a difference.
- •Stay hydrated and maintain a consistent sleep schedule.
Along with these habits, incorporating foods that help prevent cancer into your meals, such as berries, tomatoes, and leafy greens, can add further protection and support long-term ovarian health.
2. Regular gynaecological check-ups
Routine visits to your gynaecologist are essential for early detection. Regular pelvic exams, ultrasounds, and hormone tests can track PCOS progression and spot any ovarian changes early.
3. Managing hormones and insulin levels
Keeping your hormones and insulin levels balanced reduces the PCOS and ovarian cancer risk. Your doctor may recommend lifestyle changes, metformin for insulin resistance, or birth control pills to regulate hormones.
Monitoring blood sugar and hormone levels regularly helps prevent imbalances from developing into chronic issues.
4. Awareness of symptoms and timely screening
Being aware of your risk and acting early can make a significant difference in preventing complications related to both PCOS and ovarian cancer.
Your next steps if you're worried - can PCOS cause ovarian cancer?
If you’ve ever wondered about whether POS can cause ovarian cancer, the short answer is, not directly. But the hormonal, metabolic, and inflammatory changes that come with PCOS may slightly increase the ovarian cancer risk over time. The key is early management.
So, can PCOS cause ovarian cancer? No, but staying informed helps you take control of your health.
FAQs on can PCOS cause ovarian cancer
No, the cysts in PCOS are not cancerous. They are immature follicles, unlike the abnormal growths seen in ovarian cancer.
Yes, symptoms like bloating, irregular periods, or pelvic pain can overlap, which is why ovarian cancer is mistaken for PCOS.
PCOS is a hormonal disorder causing irregular cycles and cyst formation, while ovarian cancer involves uncontrolled cell growth in the ovaries.
While it’s inaccurate to say PCOS causes ovarian cancer, research shows that the hormonal and metabolic changes linked to PCOS may increase ovarian cancer risk slightly.
