

Stomach Cancer
What is Stomach Cancer?
Stomach cancer, or gastric cancer, develops from the lining of the stomach. The most prevalent form—adenocarcinoma—is accountable for 90–95% of all cases and develops in the glandular cells that produce mucus and digestive juices. These cancers are also divided into two broad subtypes: intestinal, which tends to form gland-like structures and is often associated with environmental factors; and diffuse, which is more aggressive in character and often associated with genetic mutations.

Stomach Cancer Types
Adenocarcinoma (90–95%)
•Includes intestinal and diffuse types.
Gastrointestinal Stromal Tumors (GISTs)
•Arise from the stomach's connective tissue.
Lymphomas
•Cancers involving the immune system, rarely presenting in the lining of the stomach.
Carcinoid Tumors
•Arise from hormone-secreting cells of the stomach.
Stomach Cancer Symptoms
- •Frequent or long-lasting indigestion or heartburn that does not improve with over-the-counter medications.
What’s Notable
The fifth most common cancer globally
The fourth most common cause of cancer-related deaths globally.
In 2022, there were over 1 million new cases and approximately 770,000 deaths.
When to Seek Help
You should seek medical help if you have persistent symptoms such as ongoing indigestion or heartburn that does not improve, unexplained weight loss, stomach pain or discomfort, difficulty swallowing, vomiting (especially if blood is present), black or tarry stools, or abdominal swelling. If these symptoms last more than two to three weeks or worsen, especially in combination, timely evaluation by a healthcare professional is essential for early diagnosis and effective treatment.
Stomach Cancer Causes & Risk Factors
Helicobacter pylori (H. pylori) Infection
A major cause of chronic gastritis and gastric cancer development.
Diet
Overindulgence in smoked, salted, and pickled food; poor fruit and vegetable consumption.
High Smoking and Alcohol Consumption
Heavy smoking and heavy alcohol use can almost double the risk.
Family History and Genetics
Lynch syndrome genetic conditions increase susceptibility.
Chronic Stomach Illnesses
Ulcers, gastritis, intestinal metaplasia, and obesity—specifically abdominal obesity.
Exposure in Work Life
Exposure to poisonous substances in coal, metal, and rubber manufacturing.
Stomach Cancer Diagnosis
Initial Symptoms & Check-up
Step 1: Initial Symptoms & Check-up
Symptoms: stomach pain, indigestion, nausea, weight loss.
Action: Physical exam, medical history review.
Stomach Cancer Treatment
Chemotherapy
What it does:
Kills rapidly dividing cancer cells in the body.
Common drugs:
Cisplatin, Fluorouracil (5-FU), Oxaliplatin.
Side effects:
Nausea, fatigue, hair loss, low blood counts.
Targeted Therapy
What it does :
Blocks specific molecules involved in cancer growth.
Common drugs:
Trastuzumab (Herceptin), Ramucirumab.
Side effects:
Fatigue, high blood pressure, bleeding.
Immunotherapy
What it does:
Boosts the immune system to attack cancer cells.
Common drugs:
Pembrolizumab (Keytruda).
Side effects:
Fatigue, skin rash, inflammation of organs.
Management & Prevention
Rest and Healing
•Allow your body to recover after treatment, whether surgery, chemotherapy, or radiation therapy.
Gradual Activity
•Begin with light activities and slowly increase your physical exercise as tolerated to restore strength.
Nutrition
•Focus on a balanced, nutrient-rich diet to support healing, manage side effects, and maintain energy.
Symptom Management
•Work closely with your healthcare team to address symptoms like nausea, fatigue, or pain.
Stomach Cancer Types
Adenocarcinoma (90–95%)
•Includes intestinal and diffuse types.
Gastrointestinal Stromal Tumors (GISTs)
•Arise from the stomach's connective tissue.
Lymphomas
•Cancers involving the immune system, rarely presenting in the lining of the stomach.
Carcinoid Tumors
•Arise from hormone-secreting cells of the stomach.
Stomach Cancer Symptoms
- •Frequent or long-lasting indigestion or heartburn that does not improve with over-the-counter medications.
What’s Notable
The fifth most common cancer globally
The fourth most common cause of cancer-related deaths globally.
In 2022, there were over 1 million new cases and approximately 770,000 deaths.
When to Seek Help
You should seek medical help if you have persistent symptoms such as ongoing indigestion or heartburn that does not improve, unexplained weight loss, stomach pain or discomfort, difficulty swallowing, vomiting (especially if blood is present), black or tarry stools, or abdominal swelling. If these symptoms last more than two to three weeks or worsen, especially in combination, timely evaluation by a healthcare professional is essential for early diagnosis and effective treatment.
Stomach Cancer Causes & Risk Factors
Helicobacter pylori (H. pylori) Infection
A major cause of chronic gastritis and gastric cancer development.
Diet
Overindulgence in smoked, salted, and pickled food; poor fruit and vegetable consumption.
High Smoking and Alcohol Consumption
Heavy smoking and heavy alcohol use can almost double the risk.
Family History and Genetics
Lynch syndrome genetic conditions increase susceptibility.
Chronic Stomach Illnesses
Ulcers, gastritis, intestinal metaplasia, and obesity—specifically abdominal obesity.
Exposure in Work Life
Exposure to poisonous substances in coal, metal, and rubber manufacturing.
Stomach Cancer Diagnosis
Initial Symptoms & Check-up
Step 1: Initial Symptoms & Check-up
Symptoms: stomach pain, indigestion, nausea, weight loss.
Action: Physical exam, medical history review.
Stomach Cancer Treatment
Chemotherapy
What it does:
Kills rapidly dividing cancer cells in the body.
Common drugs:
Cisplatin, Fluorouracil (5-FU), Oxaliplatin.
Side effects:
Nausea, fatigue, hair loss, low blood counts.
Targeted Therapy
What it does :
Blocks specific molecules involved in cancer growth.
Common drugs:
Trastuzumab (Herceptin), Ramucirumab.
Side effects:
Fatigue, high blood pressure, bleeding.
Immunotherapy
What it does:
Boosts the immune system to attack cancer cells.
Common drugs:
Pembrolizumab (Keytruda).
Side effects:
Fatigue, skin rash, inflammation of organs.
Management & Prevention
Rest and Healing
•Allow your body to recover after treatment, whether surgery, chemotherapy, or radiation therapy.
Gradual Activity
•Begin with light activities and slowly increase your physical exercise as tolerated to restore strength.
Nutrition
•Focus on a balanced, nutrient-rich diet to support healing, manage side effects, and maintain energy.
Symptom Management
•Work closely with your healthcare team to address symptoms like nausea, fatigue, or pain.
Why Choose Everhope Stomach Cancer?
At Everhope Oncology, we see prostate cancer as more than a diagnosis; it’s a unique journey. With expert care, empathy, and the latest treatments, we stand with you at every step, guiding you toward strength, hope, and healing.
55K
New cases of were diagnosed in India
48K
Individuals lost their lives due to stomach cancer.
3rd
Most common reason for cancer deaths among men is stomach cancer.
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