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Blood Cancer

What is Blood Cancer?

Blood cancers include types such as leukemia, lymphoma, and myeloma, which affect the blood, bone marrow, and lymphatic system. Blood cancers could be defined as the cancers that disrupt the development of blood cells and impair immune function, leading to significant health challenges. Blood cancers can occur at any age and often go undetected in the early stages due to subtle or absent symptoms.

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Blood Cancer Types

  • Leukemia

    A cancer of the blood and bone marrow, leukemia causes abnormal white blood cell production. It can be acute or chronic and affects both children and adults, weakening the immune system and hindering blood function.

  • Lymphoma

    Lymphoma originates in the lymphatic system, where it disrupts the body’s ability to fight infections. It includes two main types—Hodgkin and Non-Hodgkin lymphoma—affecting lymph nodes, spleen, and other organs.

  • Multiple Myeloma

    This cancer forms in plasma cells, a type of white blood cell that produces antibodies. It weakens bones, impairs immunity, and disrupts normal blood cell production in the bone marrow.

  • Myelodysplastic Syndromes (MDS)

    MDS refers to a group of disorders where the bone marrow doesn’t produce enough healthy blood cells. It may progress to acute myeloid leukemia and often causes fatigue, infections, and bleeding issues.

  • Myeloproliferative Neoplasms (MPNs)

    MPNs are rare blood cancers in which the bone marrow produces too many red blood cells, white blood cells, or platelets. This overproduction can lead to blood clots, bleeding, and progression to leukemia

Blood Cancer Symptoms

  • Constant tiredness that doesn’t improve with rest could signal abnormal blood cell production.

  • A weak immune system due to cancerous white blood cells can cause recurring fevers and infections.

  • Minor bumps causing bruises or frequent nosebleeds may indicate low platelet counts

  • Painless lumps in the neck, armpits, or groin can be early signs of lymphoma.

  • Sudden loss of weight without dieting may point to cancer-related metabolic changes.

What’s Notable

cancer-symptoms

Blood Cancers account for approximately 8-10% of cancers in India

cancer-symptoms

Leukemia is the most frequent childhood cancer

When to Seek Help

Seek immediate medical help if you experience unexplained bruising or bleeding, persistent fatigue, frequent infections, shortness of breath, unexplained weight loss, or a fever of 38°C or higher - for longer than 2 weeks.

Blood Cancer Causes & Risk Factors

Genetic Mutations

Chromosomal or gene mutations such as the Philadelphia chromosome may predispose individuals to leukemia or other cancers of the blood.

Family History

Having a first-degree relative with blood cancer may slightly increase your own risk.

Radiation Exposure

High exposure to ionizing radiation—such as with cancer treatment involving radiation therapy or nuclear power plant accidents—can harm bone marrow cells and lead to leukemia.

Chemical Exposure

Long-term exposure to industrial solvents such as benzene, which is employed in chemical and rubber production, has resulted in increased leukemia risk.

Weakened Immune System

HIV/AIDS patients, organ recipients who receive an organ transplant, or autoimmune disorders can expose an individual to some types of blood cancers.

Viral Infections

Certain viruses such as Epstein-Barr virus (EBV) and human T-cell leukemia virus (HTLV-1) have a causative association with some types of lymphoma.

Smoking

Cigarette smoke also includes benzene and other chemicals that are established carcinogens and can cause an increased risk of acute myeloid leukemia (AML).

Some Blood Disorders

Aplastic anemia or myelodysplastic syndromes may develop into leukemia if not treated well.

Blood Cancer Diagnosis

Early Symptoms & Check Up

Step 1: Early Symptoms & Check-up

  1. Common symptoms: fatigue, spontaneous bruising or bleeding, frequent infections, swollen lymph glands
  2. Physician performs a physical exam and reviews medical history

Your role: Share any changes you’ve noticed openly.

Blood Tests

Step 2: Blood Tests

  • Tests include Complete Blood Count (CBC) and peripheral blood smear
  • Abnormal blood counts may indicate blood cancer

Biopsy (Definitive Test)

Step 3: Bone Marrow Biopsy

  • Confirms the diagnosis and identifies the specific type of blood cancer

Imaging Tests

Step 4: Imaging Tests

  • PET, CT, or MRI scans assess the extent and spread of cancer, especially for lymphoma

Genetic & Molecular Testing

Step 5: Genetic & Molecular Testing

  • Detects mutations in cancer cells and helps guide targeted treatment decisions

Staging & Risk Stratification

Step 6: Staging & Risk Stratification

  • Determines the stage and risk level of cancer (e.g., Rai staging for CLL, Ann Arbor staging for lymphoma)
  • Important for prognosis and treatment planning

Step 7: Next Steps

Step 7: Next Steps

  • Oncology team formulates a personalized treatment plan based on cancer type, stage, and overall health

Blood Cancer Treatment & Therapy

Chemotherapy

What it does:

Cancers-killing medicines that attack fast-growing blood cells

Treated for:

Most blood cancers (leukemia, lymphoma, myeloma)

Recovery:

Varied; includes many cycles spanning weeks to months

Targeted Therapy

What it does :

Medicines that attack distinct genetic markers in cancer cells

Treated for:

Cancers with known mutations (e.g., CML, specific lymphomas)

Common medications:

Imatinib, Ibrutinib, Rituximab

Recovery:

Based on response and cancer type

Immunotherapy

What it does:

Strengthens the immune system to recognize and destroy cancer

Used for:

Some leukemias and lymphomas

Drugs used:

CAR T-cell therapy, Blinatumomab, Nivolumab

Recovery:

Extensive monitoring required because of immune side effects

External Beam Radiation

What it does:

Uses focused high-energy X-rays to shrink swollen lymph nodes, liver, or spleen

Treated for:

Chronic Lymphocytic Leukemia (CLL) and localized symptoms

Common features:

Quick, painless outpatient procedure lasting just a few minutes

Recovery:

Minimal downtime; mild fatigue or skin changes may occur

Total Body Irradiation (TBI)

What it does:

Exposes the whole body to radiation to suppress immunity and destroy residual cancer

Treated for:

Leukemia patients preparing for chemotherapy and stem cell transplants

Common features:

Often combined with chemotherapy in transplant prep

Recovery:

Requires hospital stay; immune support and close monitoring needed

Total Marrow Irradiation (TMI)

What it does:

Precisely targets bone marrow—the source of cancerous cells—while sparing healthy organs

Treated for:

Leukemia patients undergoing stem cell transplant

Common methods:

Delivered using TomoTherapy for high precision

Recovery:

Better tolerated than TBI; may reduce long-term side effects

Autologous Stem Cell Transplant

What it does:

Uses the patient’s own stem cells to restore bone marrow after high-dose chemotherapy or radiation

Treated for:

Multiple myeloma, some lymphomas, and select leukemias

Common features:

Cells collected, stored, then reinfused after treatment

Recovery:

Requires hospital stay; risk of infections until immune system recovers

Allogeneic Stem Cell Transplant

What it does:

Uses stem cells from a matched donor to replace diseased bone marrow and boost immune response

Treated for:

Acute and chronic leukemias, some lymphomas, and myelodysplastic syndromes

Common features:

Requires matching donor; may trigger graft-versus-host disease (GVHD)

Recovery:

Longer hospital stay; close monitoring for complications and immune recovery

Haploidentical Stem Cell Transplant

What it does:

Uses partially matched stem cells from a family member when a fully matched donor isn’t available

Treated for:

Leukemia and lymphomas when matched donor unavailable

Common features:

Expands donor pool; specialized treatments reduce rejection risk

Recovery:

Similar to allogeneic transplant but with tailored immune suppression

Combination Therapy

Goal:

Improve treatment success with more than one type of medication

What it is:

Chemo + immunotherapy or special medications

Used for:

Relapse or refractory disease

Palliative Care

Goal:

Improve quality of life and relieve symptoms

Used for:

Advanced disease or inability to do curative therapy

Management & Prevention

  • Side Effects

    Manage fatigue and nausea with prescribed medications and hydration

  • Regular Checkups

    Routine follow-ups to track progress and prevent complications

  • Follow-Up Care

    Regular scans and tests keep you on track and catch any changes early.

  • Counseling

    Access professional help to manage emotional challenges

  • Peer Support

    Join support groups for connection and shared healing

  • Mindfulness:

    Practice meditation, deep breathing, or journaling to reduce stress

  • Healthy Diet

    Eat protein-rich, immunity-boosting foods like eggs, dals, fruits

  • Light Exercise

    Engage in gentle activity like walking, yoga, or stretching

  • Infection Safety

    Follow hygiene practices and avoid crowds to stay protected

Why Choose Everhope For Blood Cancer?

At Everhope, our experts support your proactive care with advanced treatment — guiding you with knowledge, hope, and healing.

1M

blood cancer deaths globally

70,000

blood cancer deaths annually in India

1 Indian

is diagnosed with a blood cancer every 5 minutes

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FAQs on Blood Cancer

No question is too small when it comes to your care

Yes! While some blood cancers are more common in adults, others like leukaemia can affect children too — it doesn’t discriminate by age.

No, blood cancer is not contagious. You cannot catch it from someone else like a cold or flu

It varies — some blood cancers progress slowly over years, while others can grow quickly and need urgent treatment.

While genetics play a big role, avoiding smoking and limiting exposure to harmful chemicals can lower your risk.

No! Many people live long, healthy lives after treatment — early diagnosis and modern therapies have improved survival rates dramatically.

Sometimes it can return, but ongoing monitoring and advances in treatment help manage relapses effectively

Not always. Depending on the type and stage, treatments can include targeted drugs, immunotherapy, or even stem cell transplants instead.

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